A new study by Canadian researchers published in Environmental Health Perspectives shows a link between living in polluted areas and incidence of breast cancer. Particulate matter has been conclusively linked to COPD and other respiratory diseases like chronic bronchitis as well as heart disease even, but this is the first time we’ve seen that breast cancer is another possible outcome. Fine particulate matter is probably the top reason we recommend that everyone invest in air purifiers.

"We've been watching breast cancer rates go up for some time, "says study co-author Dr. Mark Goldberg, a researcher at The RI MUHC. "Nobody really knows why, and only about one third of cases are attributable to known risk factors. Since no-one had studied the connection between air pollution and breast cancer using detailed air pollution maps, we decided to investigate it."

Dr. Goldberg and his colleagues approached the problem by combining data from several studies. First, they used the results of their 2005-2006 study to create two air pollution "maps" showing levels of nitrogen dioxide (NO₂), a by-product of vehicular traffic, in different parts of Montreal in 1996 and 10 years earlier in 1986.

Then, they charted the home addresses of women diagnosed with breast cancer in a 1996-97 study onto the air pollution maps. Their findings were startling. The incidence of breast cancer was clearly higher in areas with higher levels of air pollution.

"We found a link between post-menopausal breast cancer and exposure to nitrogen dioxide (NO₂), which is a 'marker' for traffic-related air pollution", says Dr. Goldberg. "Across Montreal, levels of NO₂ varied between 5 ppb to over 30 ppb. We found that risk increased by about 25 per cent with every increase of NO₂ of five parts per billion. Another way of saying this is that women living in the areas with the highest levels of pollution were almost twice as likely to develop breast cancer as those living in the least polluted areas."

These disturbing results must be interpreted with great caution, warns Dr. Goldberg. "First of all, this doesn't mean NO2 causes breast cancer," he explains. "This gas is not the only pollutant created by cars and trucks, but where it is present, so are the other gases, particles and compounds we associate with traffic – some of which are known carcinogens. NO₂ is only a marker, not the actual carcinogenic agent."

A study of this kind can be subject to unknown errors. While the researchers tried to account as much as possible for them, areas of uncertainty remain. "For example, we don't know how much the women in the study were exposed to pollution while at home or at work, because that would depend on their daily patterns of activity, how much time they spend outdoors and so on," says Dr. Goldberg.

Dr. Labreche adds "Some studies published in the US have also shown possible links between cancer and air pollution. At the moment, we are not in a position to say with assurance that air pollution causes breast cancer. However, we can say that the possible link merits serious investigation. From a public health standpoint, this possible link also argues for actions aimed at reducing traffic-related air pollution in residential areas."

Source: Environmental Health Perspectives, courtesy of Physorg